Path to Relief: A Guide to Diabetic Peripheral Neuropathy Treatment

Diabetic Peripheral Neuropathy Treatment

DPN (Diabetic Peripheral Neuropathy) is a condition characterized by nerve damage, often affecting the extremities, and it can lead to symptoms such as pain, tingling, and numbness. Managing diabetic peripheral neuropathy is crucial for maintaining a good quality of life, and fortunately, there are various treatment options available. In this comprehensive guide, we will explore the different aspects of diabetic peripheral neuropathy treatment, from lifestyle adjustments to medical interventions, providing valuable insights to help individuals find relief.

What Is Diabetic Peripheral Neuropathy?

What Is Diabetic Peripheral Neuropathy?Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes characterized by nerve damage, primarily affecting the extremities such as the feet and legs. The condition arises due to prolonged exposure to high levels of blood sugar, which can lead to injury and dysfunction of the peripheral nerves. These nerves play a crucial role in transmitting signals between the central nervous system and the rest of the body.

As a result of DPN, individuals may experience symptoms such as pain, tingling, and numbness in the affected areas. Over time, nerve damage can also lead to sensory loss, increasing the risk of injuries and infections, particularly in the feet.

The development of DPN is often gradual. Its symptoms may vary from mild discomfort to severe, debilitating pain. Factors such as poor blood sugar control, smoking, and genetics can contribute to the risk of developing diabetic peripheral neuropathy. Early detection and proactive management are essential to prevent further progression of the condition and improve the overall quality of life.

What Are Some Diabetic Peripheral Neuropathy Treatment Options?

Several medical approaches are available for the treatment of Diabetic Peripheral Neuropathy (DPN). It’s important to note that the effectiveness of these treatments can vary from person to person, and a healthcare professional should be consulted to determine the most suitable options. Here are some common diabetic peripheral neuropathy treatment options:


  • Antidepressants: Medications commonly prescribed for depression, such as amitriptyline and duloxetine, are effective in managing neuropathic pain associated with diabetic peripheral neuropathy. These drugs work by altering the way the body perceives and processes pain signals, providing relief to individuals experiencing discomfort or pain due to nerve damage.
  • Anticonvulsants: Certain anticonvulsant medications, including gabapentin and pregabalin, are known to help manage nerve pain. These drugs stabilize electrical activity in the brain and affect the way nerves send signals to the brain. As a result, they can reduce the intensity of pain caused by damaged nerves in individuals with diabetic peripheral neuropathy.

Pain Relievers

  • Over-the-counter Pain Medications: Over-the-counter pain relievers, such as acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs), may be recommended for individuals with mild to moderate pain associated with diabetic peripheral neuropathy. While these medications can provide relief, their long-term use should be monitored, and individuals should consult their healthcare providers for guidance.

Topical Treatments

  • Lidocaine Patches or Creams: Topical treatments containing lidocaine can be applied directly to the skin over the affected area. Lidocaine is a local anesthetic that temporarily numbs the skin and underlying tissues, offering relief from pain and discomfort associated with diabetic peripheral neuropathy.

Opioid Medications

  • Stronger Pain Medications: In cases where diabetic peripheral neuropathy causes severe pain that is not adequately controlled with other medications, opioids may be considered. However, the use of opioids is typically reserved for situations where other treatments have proven ineffective. And the potential risks of dependence and side effects are carefully weighed by healthcare professionals.

Neuropathy-specific Medications

Neuropathy-specific Medications

  • Nerve Growth Factor (NGF) Inhibitors: Emerging as a potential avenue for treating neuropathic pain, NGF inhibitors are medications that target nerve growth factor, a protein involved in the growth and survival of nerve cells. Research is ongoing to assess the efficacy and safety of these medications for managing diabetic peripheral neuropathy, offering hope for more targeted and effective treatments in the future.

Alpha-lipoic Acid

  • Supplements: Alpha-lipoic acid (ALA) is a naturally occurring antioxidant that has been explored for its potential benefits in managing diabetic peripheral neuropathy. ALA may help reduce oxidative stress, a factor contributing to nerve damage. Some studies suggest that ALA supplementation may improve nerve function and alleviate symptoms.

Transcutaneous Electrical Nerve Stimulation (TENS)

  • Medical Devices: Transcutaneous Electrical Nerve Stimulation (TENS) involves the use of a small, battery-operated device that delivers low-voltage electrical currents to the skin via electrodes. This electrical stimulation may help disrupt or reduce pain signals sent to the brain, offering relief for individuals with diabetic peripheral neuropathy. TENS units are portable and can be used at home under the guidance of a healthcare professional or physical therapist.

Physical Therapy

  • Therapeutic Exercises: Physical therapy plays a crucial role in managing diabetic peripheral neuropathy by addressing physical limitations and promoting overall well-being. Therapeutic exercises designed by a physical therapist aim to improve muscle strength, flexibility, and balance, reducing the risk of falls and injuries. Additionally, physical therapy can enhance circulation and nerve function in affected areas.

Individuals with diabetic peripheral neuropathy can benefit from a tailored exercise program that takes into account their specific symptoms and challenges. Regular sessions with a physical therapist can contribute to better overall mobility and function, complementing other treatment approaches.

What Vitamins Are Helpful In Diabetic Peripheral Neuropathy Treatment?

Several vitamins and supplements have been studied for their potential benefits in managing diabetic peripheral neuropathy (DPN). It’s important to note that individual responses to these supplements can vary, and their effectiveness may depend on factors such as the severity of neuropathy and overall health. Here are some vitamins and supplements that have shown promise in DPN treatment:

Alpha-lipoic Acid (ALA)

ALA is a potent antioxidant that may help reduce oxidative stress and inflammation, both of which can contribute to nerve damage. Some studies have suggested that ALA supplementation may improve symptoms of diabetic peripheral neuropathy, including pain and numbness.

Vitamin B Complex

B vitamins, especially B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) play a crucial role in nerve health. Deficiencies in these vitamins have been linked to neuropathy. Vitamin B supplements, either individually or as a complex, are commonly used in the management of diabetic peripheral neuropathy.

Vitamin D

Adequate levels of vitamin D are essential for overall nerve function and health. Research has indicated that individuals with diabetes, including those with diabetic peripheral neuropathy, may have lower vitamin D levels. Supplementation with vitamin D may help support nerve health and potentially alleviate symptoms.

Vitamin E

Vitamin E is an antioxidant that may help protect nerves from damage caused by oxidative stress. While more research is needed, some studies suggest that vitamin E supplementation may have a positive impact on nerve function and symptoms in individuals with diabetic peripheral neuropathy.

Omega-3 Fatty Acids

Omega-3 fatty acids, found in fish oil and certain plant sources, have anti-inflammatory properties. Chronic inflammation is associated with neuropathy, and omega-3 supplements may help reduce inflammation and support nerve health.


Acetyl-L-carnitine is an amino acid that plays a role in energy production. Some studies suggest that supplementation may have a positive effect on nerve function and symptoms in individuals with diabetic neuropathy.


Magnesium is involved in various physiological processes, including nerve function. Some individuals with diabetes may have lower magnesium levels, and supplementation may help manage neuropathic symptoms.

It’s crucial to emphasize that while these vitamins and supplements may offer potential benefits, they should not be used as a substitute for medical treatment. Always consult with a healthcare professional before adding any new supplements to your regimen, as they can interact with medications or have adverse effects, especially in high doses.

Does Neuropathy From Diabetes Go Away?

Does Neuropathy From Diabetes Go Away?Unfortunately, diabetic neuropathy typically does not completely go away. However, its progression can be slowed, and symptoms can often be managed effectively. The primary focus in managing diabetic neuropathy is on controlling and maintaining stable blood sugar levels. Well-managed blood sugar helps prevent further damage to the nerves and can sometimes alleviate symptoms. In some cases, especially if detected early, lifestyle changes can contribute to the overall management of neuropathic symptoms.

Various treatments, including medications, physical therapy, and supplements, are available to help manage the symptoms of diabetic neuropathy and improve the quality of life for affected individuals. While these approaches aim to manage symptoms, it’s crucial to acknowledge that reversing nerve damage may be challenging. Thus, emphasizes the importance of preventive measures and comprehensive diabetes care to minimize the impact of diabetic neuropathy over time. Regular monitoring and collaboration with healthcare professionals are essential to tailor an effective treatment plan for each individual’s specific needs.


In conclusion, navigating the complexities of diabetic peripheral neuropathy demands a multifaceted approach that encompasses both lifestyle adjustments and medical interventions. As explored in this comprehensive guide, understanding the nuances of diabetic neuropathy, and implementing diabetic peripheral neuropathy treatment, such as maintaining stable blood sugar levels and adopting a neuropathy-friendly lifestyle, are crucial steps toward managing this condition.

While a complete reversal of nerve damage may be challenging, the pursuit of comprehensive diabetes care, coupled with a commitment to individualized treatment plans, can significantly enhance the quality of life for those facing the daily challenges of diabetic peripheral neuropathy. Regular check-ups, open communication with healthcare professionals, and a proactive mindset are key elements in empowering individuals to improve their overall well-being.

Do you want to get rid of diabetes? Join our online diabetes treatment program and reverse Diabetes naturally through lifestyle changes such as a Personalized Diet plan, Exercise, Yoga, dieticians, and health coaches.